2026 Lexus IS 350

new

White exterior

$50,921

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$50,921

MSRP: $48,479

white exterior, palomino nuluxe and black metallic trim interior

Rear Wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Gray exterior

$50,921

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$50,921

MSRP: $48,479

gray exterior, black nuluxe and black metallic trim interior

Rear Wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

White exterior

$51,251

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$51,251

MSRP: $48,809

white exterior, black nuluxe and black metallic trim interior

Rear Wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$54,676

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$54,676

MSRP: $52,234

white exterior, white and black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2025 Lexus IS 350

new

Unknown

Gray exterior

$55,030

Jim Hudson Lexus

5.0

2025 Lexus IS 350 | new

$55,030

MSRP: $52,588

gray exterior, black nuluxe and black geometric trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$55,091

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$55,091

MSRP: $52,649

white exterior, radiant red nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Gray exterior

$61,890

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$61,890

MSRP: $59,448

gray exterior, radiant red nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2022 Lexus IS 350

used

Automatic

Eminent White Pearl exterior

$37,500

Fred Anderson Acura

4.8

2022 Lexus IS 350 | used

$37,500

eminent white pearl exterior, circuit red interior

Automatic

Rear-wheel Drive

Fred Anderson Acura

4.8

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2023 Lexus IS 350

used

Automatic

Atomic Silver exterior

$42,598

Lexus of Greenville

4.6

2023 Lexus IS 350 | used

$42,598

atomic silver exterior, black interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2024 Lexus IS 350

used

Automatic

Cloudburst Gray exterior

$43,998

Lexus of Greenville

4.6

2024 Lexus IS 350 | used

$43,998

cloudburst gray exterior, black interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

incognito exterior

$52,183

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

$52,183

MSRP: $52,183

incognito exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

Infra-Red exterior

$52,353

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

$52,353

MSRP: $52,353

infra-red exterior, black nuluxe interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

ultra white exterior

$53,133

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

$53,133

MSRP: $53,133

ultra white exterior, black nuluxe interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

cloudburst gray exterior

$53,133

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

$53,133

MSRP: $53,133

cloudburst gray exterior, black nuluxe interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2026 Lexus IS 350

new

Ultra White exterior

Not Priced

Lexus of Greenville

4.6

2026 Lexus IS 350 | new

Not Priced

ultra white exterior, black nuluxe interior

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

ultra white exterior

Not Priced

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

Not Priced

ultra white exterior, rioja red nulux interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

ultra white exterior

Not Priced

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

Not Priced

ultra white exterior, rioja red nulux interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

iridium exterior

Not Priced

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

Not Priced

iridium exterior, rioja red nulux interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

ultra white exterior

Not Priced

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

Not Priced

ultra white exterior, black nuluxe interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2025 Lexus IS 350

new

Automatic

ultra white exterior

Not Priced

Lexus of Greenville

4.6

2025 Lexus IS 350 | new

Not Priced

ultra white exterior, rioja red nulux interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.6

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2024 Lexus IS 350

used

Automatic

Gray exterior

$48,499

Escude Nissan of Greer

4.4

2024 Lexus IS 350 | used

$48,499

gray exterior, circuit red interior

Automatic

Rear-wheel Drive

Escude Nissan of Greer

4.4

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2023 Lexus IS 350

used

Automatic

Gray exterior

$38,965

Peter Boulware Toyota of Columbia

3.7

2023 Lexus IS 350 | used

$38,965

gray exterior, circuit red interior

Automatic

Rear-wheel Drive

Peter Boulware Toyota of Columbia

3.7

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2022 Lexus IS 350

used

Automatic

Blue exterior

$30,990

Automaxx Of Summerville

2.6

2022 Lexus IS 350 | used

$30,990

blue exterior, black interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

2.6

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2022 Lexus IS 350

used

Automatic

Iridium exterior

$36,900

Automaxx Of Summerville

2.6

2022 Lexus IS 350 | used

$36,900

iridium exterior, black w/black interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

2.6

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2023 Lexus IS 350

used

Automatic

Caviar exterior

$36,901

Automaxx Of Summerville

2.6

2023 Lexus IS 350 | used

$36,901

caviar exterior, circuit red interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

2.6

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2023 Lexus IS 350

used

Automatic

Caviar exterior

$43,399

Automaxx Of Summerville

2.6

2023 Lexus IS 350 | used

$43,399

caviar exterior, circuit red interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

2.6

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2021 Lexus IS 350

used

Automatic

N/A exterior

$38,990

JTs Chrysler Dodge Jeep RAM of Columbia

N/A

2021 Lexus IS 350 | used

$38,990

MSRP: $39,990

n/a exterior, n/a interior

Automatic

Rear-wheel Drive

JTs Chrysler Dodge Jeep RAM of Columbia

N/A

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Lexus IS 350 vehicles for Sale in South Carolina

27 Results

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2025 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2022 Lexus IS 350 | used

2023 Lexus IS 350 | used

2024 Lexus IS 350 | used

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2026 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2024 Lexus IS 350 | used

2023 Lexus IS 350 | used

2022 Lexus IS 350 | used

2022 Lexus IS 350 | used

2023 Lexus IS 350 | used

2023 Lexus IS 350 | used

2021 Lexus IS 350 | used