2021 Lexus IS 350

used

Automatic

Black exterior

$41,361

Jim Hudson Lexus

5.0

2021 Lexus IS 350 | used

$41,361

black exterior, white interior

Automatic

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Black exterior

$51,850

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$51,850

MSRP: $49,408

black exterior, black nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Gray exterior

$52,350

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,350

MSRP: $49,908

gray exterior, black nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$52,350

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,350

MSRP: $49,908

white exterior, palomino nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$52,350

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,350

MSRP: $49,908

white exterior, black nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Gray exterior

$52,451

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,451

MSRP: $50,009

gray exterior, black nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Gray exterior

$52,451

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,451

MSRP: $50,009

gray exterior, black nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$52,451

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,451

MSRP: $50,009

white exterior, palomino nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$52,451

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$52,451

MSRP: $50,009

white exterior, black nuluxe and black metallic trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2025 Lexus IS 350

used

Automatic

Blue exterior

$53,138

Jim Hudson Lexus

5.0

2025 Lexus IS 350 | used

$53,138

blue exterior, black interior

Automatic

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Silver exterior

$55,420

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$55,420

MSRP: $52,978

silver exterior, black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Red exterior

$55,515

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$55,515

MSRP: $53,073

red exterior, white and black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Silver exterior

$55,521

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$55,521

MSRP: $53,079

silver exterior, black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$55,521

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$55,521

MSRP: $53,079

white exterior, radiant red nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Silver exterior

$57,496

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$57,496

MSRP: $55,054

silver exterior, black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

White exterior

$61,540

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$61,540

MSRP: $59,098

white exterior, black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2026 Lexus IS 350

new

Unknown

Red exterior

$61,736

Jim Hudson Lexus

5.0

2026 Lexus IS 350 | new

$61,736

MSRP: $59,294

red exterior, black nuluxe and satin trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

5.0

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2023 Lexus IS 350

used

Automatic

Ultra White exterior

$43,231

Fred Anderson Toyota of Charleston

4.9

2023 Lexus IS 350 | used

$43,231

ultra white exterior, black interior

Automatic

Rear-wheel Drive

Fred Anderson Toyota of Charleston

4.9

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2016 Lexus IS 350

used

Automatic

Ultra White exterior

$23,498

Steve White Volkswagen Audi - Greenville

4.7

2016 Lexus IS 350 | used

$23,498

ultra white exterior, black interior

Automatic

Rear-wheel Drive

Steve White Volkswagen Audi - Greenville

4.7

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2022 Lexus IS 350

used

Automatic

Atomic Silver exterior

$36,396

Fairway Ford, Inc.

4.7

2022 Lexus IS 350 | used

$36,396

MSRP: $40,900

atomic silver exterior, white interior

Automatic

Rear-wheel Drive

Fairway Ford, Inc.

4.7

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2024 Lexus IS 350

used

Automatic

Iridium exterior

$43,970

Herlong Chevrolet

4.6

2024 Lexus IS 350 | used

$43,970

iridium exterior, black interior

Automatic

Rear-wheel Drive

Herlong Chevrolet

4.6

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2023 Lexus IS 350

used

Automatic

Gray exterior

$40,998

CarMax Columbia

3.8

2023 Lexus IS 350 | used

$40,998

gray exterior, red interior

Automatic

Rear-wheel Drive

CarMax Columbia

3.8

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2024 Lexus IS 350

used

Automatic

Iridium exterior

$38,622

Automaxx Of Summerville

3.6

2024 Lexus IS 350 | used

$38,622

iridium exterior, black interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

3.6

Contact Seller

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2022 Lexus IS 350

used

Automatic

Silver exterior

$41,255

Automaxx Of Summerville

3.6

2022 Lexus IS 350 | used

$41,255

silver exterior, white w/black interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

3.6

Contact Seller

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2023 Lexus IS 350

used

Automatic

Ultra White exterior

$40,698

INFINITI of Greenville

N/A

2023 Lexus IS 350 | used

$40,698

ultra white exterior, black interior

Automatic

Rear-wheel Drive

INFINITI of Greenville

N/A

Contact Seller

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2023 Lexus IS 350

used

Automatic

Ultra White exterior

$46,667

INFINITI of Greenville

N/A

2023 Lexus IS 350 | used

$46,667

ultra white exterior, circuit red interior

Automatic

Rear-wheel Drive

INFINITI of Greenville

N/A

Contact Seller

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2024 Lexus IS 350

used

Automatic

Infrared exterior

$47,353

Mercedes-Benz of Mount Pleasant

N/A

2024 Lexus IS 350 | used

$47,353

infrared exterior, black interior

Automatic

All-wheel Drive

Mercedes-Benz of Mount Pleasant

N/A

Contact Seller

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2026 Lexus IS 350

new

Automatic

Cloudburst Gray exterior

$50,186

Lexus of Greenville

N/A

2026 Lexus IS 350 | new

$50,186

MSRP: $50,186

cloudburst gray exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

N/A

Contact Seller

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2026 Lexus IS 350

new

Automatic

ultra white exterior

$50,399

Lexus of Greenville

N/A

2026 Lexus IS 350 | new

$50,399

MSRP: $50,399

ultra white exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

N/A

Contact Seller

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2026 Lexus IS 350

new

Automatic

Ultra White exterior

$50,457

Lexus of Greenville

N/A

2026 Lexus IS 350 | new

$50,457

MSRP: $50,457

ultra white exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

N/A

Contact Seller

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Lexus IS 350 vehicles for Sale in South Carolina

49 Results

2021 Lexus IS 350 | used

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2025 Lexus IS 350 | used

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2023 Lexus IS 350 | used

2016 Lexus IS 350 | used

2022 Lexus IS 350 | used

2024 Lexus IS 350 | used

2023 Lexus IS 350 | used

2024 Lexus IS 350 | used

2022 Lexus IS 350 | used

2023 Lexus IS 350 | used

2023 Lexus IS 350 | used

2024 Lexus IS 350 | used

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new

2026 Lexus IS 350 | new